Risk Ratio proc genmod predictor variable has multiple levels - sas

I am using proc genmod to estimate risk ratios. Two of my predictor variables have more than 2 levels. My gender variable is ‘male’, ‘female’, ‘other’ and race is ‘white’,’non-hispanic black’, ‘hispanic’. Here is how I set up the model. I get only 1 risk ratio. Is it possible to risk ratio for each level of the predictor variable? I have not done this before, so any advice is appreciated.
Thanks.
Proc genmod data=rr_genmod;
Class gender(ref=’male’) race (ref=’white’);
Model outcomeA(ref=’1’)=gender race/ dist=binomial link=log;
ESTIMATE 'BETA' GENDER 1-1/EXP;
ESTIMATE 'BETA' RACE 1-1/EXP;
RUN;

I would start with the LSMEANS then perhaps LSMESTIMATE for more complex estimates. The syntax is would be something like this.
LSMEANS GENDER RACE / DIFF CL EXP;
There are other options that may be useful but you should consult the documentation for those details.

Related

Detailed of predictions on proc logistic

I am implementing a logit model in a database of households using as dependent variable the classification of poor or not poor household (1 if it is poor, 0 if it is not):
proc logistic data=regression;
model poor(event="1") = variable1 variable2 variable3 variable4;
run;
Using the proc logistic in SAS, I obtained the table "Association of predicted probabilities and observed responses" that allows me to know the concordant percentage. However, I require detailed information of how many households are classified poor adequately, in this way:
I will appreciate your help with this issue.
Add the CTABLE option to your MODEL statement.
model poor(event="1") = variable1 variable2 variable3 variable4 / ctable;
CTABLE classifies the input binary response observations according to
whether the predicted event probabilities are above or below some
cutpoint value z in the range . An observation is predicted as an
event if the predicted event probability exceeds or equals z. You can
supply a list of cutpoints other than the default list by specifying
the PPROB= option. Also, you can compute positive and negative
predictive values as posterior probabilities by using Bayes’ theorem.
You can use the PEVENT= option to specify prior probabilities for
computing these statistics. The CTABLE option is ignored if the data
have more than two response levels. This option is not available with
the STRATA statement.
For more information, see the section Classification Table.

Linear Regression: Finding Significant Class Variables Using SAS

I'm attempting to use SAS to do a pretty basic regression problem but I'm having trouble getting the full set of results.
I'm using a data set that includes professors' overall quality (the dependent variable) and has the following independent variables: gender, numYears, pepper, discipline, easiness, and rateInterest.
I'm using the code below to generate the analysis of the data set:
proc glm data=WORK.IMPORT;
class gender pepper discipline;
model quality = gender numYears pepper discipline easiness raterInterest;
run;
I get the following results, which is mostly what I need, EXCEPT that I would like to see exactly which responses from the class variables (gender, pepper, discipline) are significant.
From these results, I can see that easiness, rateInterest, pepper, and discipline are significant; however, I'd like to see which specific values of pepper and discipline are significant. For example, pepper was answered as a 'yes' or 'no' by the student. I'd like to see if quality correlates specifically to pepperyes or pepperno. Can anyone give me some advice about how to alter my code to return a breakdown of the class variables?
Here is also a link to the dataset, in case it's needed for reference:
https://drive.google.com/file/d/1Kc9cb_n-l7qwWRNfzXtZi5OsiY-gsYZC/view?usp=sharingRateprof
I really, truly appreciate any assistance!
Add the solution option to your model statement to break out statistics of each class variable; however, reference parameterization is not available in proc glm, and will cause biased estimates. There are ways around this to continue using proc glm, but the simplest solution is to use proc glmselect instead. proc glmselect allows you to specify reference parameterization. Use the selection=none option to disable variable selection.
proc glmselect data=WORK.IMPORT;
class gender(ref='female') pepper discipline / param=reference;
model quality = gender numYears pepper discipline easiness raterInterest / selection=none;
run;
The interpretation of this would be:
All other variables held constant, females affect the quality rating by
-0.046782 units compared to males. This variable is not statistically significant.
The breakdown of each class level is a comparison to a reference value. By default, the reference value selected is the last level after all class values are internally sorted. You can specify a reference using the ref= option after each class variable. For example, if you wanted to use females as a reference value instead of males:
proc glmselect data=WORK.IMPORT;
class gender(ref='female') pepper discipline;
model quality = gender numYears pepper discipline easiness raterInterest / selection=none;
run;
Note that you can also do this with prox mixed. For this specific purpose, the preference is up to you based on the output style that you like. proc mixed is a more flexible way to run regressions, but would be a bit overkill here.
proc mixed data=import;
class gender pepper discipline;
model quality = gender numYears pepper discipline easiness raterInterest / solution;
run;

Offsetting Oversampling in SAS for rare events in Logistic Regression

Can anyone help me understand the Premodel and Postmodel adjustments for Oversampling using the offset method ( preferably in Base SAS in Proc Logistic and Scoring) in Logistic Regression .
I will take an example. Considering the traditional Credit scoring model for a bank, lets say we have 10000 customers with 50000 good and 2000 bad customers. Now for my Logistic Regression I am using all 2000 bad and random sample of 2000 good customers. How can I adjust this oversampling in Proc Logistic using options like Offset and also during scoring. Do you have any references with illustrations on this topic?
Thanks in advance for your help!
Ok here are my 2 cents.
Sometimes, the target variable is a rare event, like fraud. In this case, using logistic regression will have significant sample bias due to insufficient event data. Oversampling is a common method due to its simplicity.
However, model calibration is required when scores are used for decisions (this is your case) – however nothing need to be done if the model is only for rank ordering (bear in mind the probabilities will be inflated but order still the same).
Parameter and odds ratio estimates of the covariates (and their confidence limits) are unaffected by this type of sampling (or oversampling), so no weighting is needed. However, the intercept estimate is affected by the sampling, so any computation that is based on the full set of parameter estimates is incorrect.
Suppose the true model is: ln(y/(1-y))=b0+b1*x. When using oversampling, the b1′ is consistent with the true model, however, b0′ is not equal to bo.
There are generally two ways to do that:
weighted logistic regression,
simply adding offset.
I am going to explain the offset version only as per your question.
Let’s create some dummy data where the true relationship between your DP (y) and your IV (iv) is ln(y/(1-y)) = -6+2iv
data dummy_data;
do j=1 to 1000;
iv=rannor(10000); *independent variable;
p=1/(1+exp(-(-6+2*iv))); * event probability;
y=ranbin(10000,1,p); * independent variable 1/0;
drop j;
output;
end;
run;
and let’s see your event rate:
proc freq data=dummy_data;
tables y;
run;
Cumulative Cumulative
y Frequency Percent Frequency Percent
------------------------------------------------------
0 979 97.90 979 97.90
1 21 2.10 1000 100.00
Similar to your problem the event rate is p=0.0210, in other words very rare
Let’s use poc logistic to estimate parameters
proc logistic data=dummy_data;
model y(event="1")=iv;
run;
Standard Wald
Parameter DF Estimate Error Chi-Square Pr > ChiSq
Intercept 1 -5.4337 0.4874 124.3027 <.0001
iv 1 1.8356 0.2776 43.7116 <.0001
Logistic result is quite close to the real model however basic assumption will not hold as you already know.
Now let’s oversample the original dataset by selecting all event cases and non-event cases with p=0.2
data oversampling;
set dummy_data;
if y=1 then output;
if y=0 then do;
if ranuni(10000)<1/20 then output;
end;
run;
proc freq data=oversampling;
tables y;
run;
Cumulative Cumulative
y Frequency Percent Frequency Percent
------------------------------------------------------
0 54 72.00 54 72.00
1 21 28.00 75 100.00
Your event rate has jumped (magically) from 2.1% to 28%. Let’s run proc logistic again.
proc logistic data=oversampling;
model y(event="1")=iv;
run;
Standard Wald
Parameter DF Estimate Error Chi-Square Pr > ChiSq
Intercept 1 -2.9836 0.6982 18.2622 <.0001
iv 1 2.0068 0.5139 15.2519 <.0001
As you can see the iv estimate still close to the real value but your intercept has changed from -5.43 to -2.98 which is very different from our true value of -6.
Here is where the offset plays its part. The offset is the log of the ratio between known population and sample event probabilities and adjust the intercept based on the true distribution of events rather than the sample distribution (the oversampling dataset).
Offset = log(0.28)/(1-0.28)*(0.0210)/(1-0.0210) = 2.897548
So your intercept adjustment will be intercept = -2.9836-2.897548= -5.88115 which is quite close to the real value.
Or using the offset option in proc logistic:
data oversampling_with_offset;
set oversampling;
off= log((0.28/(1-0.28))*((1-0.0210)/0.0210)) ;
run;
proc logistic data=oversampling_with_offset;
model y(event="1")=iv / offset=off;
run;
Standard Wald
Parameter DF Estimate Error Chi-Square Pr > ChiSq
Intercept 1 -5.8811 0.6982 70.9582 <.0001
iv 1 2.0068 0.5138 15.2518 <.0001
off 1 1.0000 0 . .
From here all your estimates are correctly adjusted and analysis & interpretation should be carried out as normal.
Hope its help.
This is a great explanation.
When you oversample or undersample in the rare event experiment, the intercept is impacted and not slope. Hence in the final output , you just need to adjust the intercept by adding offset statement in proc logistic in SAS. Probabilities are impacted by oversampling but again, ranking in not impacted as explained above.
If your aim is to score your data into deciles, you do not need to adjust the offset and can rank the observations based on their probabilities of the over sampled model and put them into deciles (Using Proc Rank as normal). However, the actual probability scores are impacted so you cannot use the actual probability values. ROC curve is not impacted as well.

SAS: choosing the right model

I'm getting a bit lost in alle the possible ways to find association...
I have a dataset in which my subjects are categorized 1, 2 or 3 (depending on genotype polymorphisms). I want to know the association of either polymorphism with ballistic strength (which is a continuous variable).
Since I have one continous independent variable (strength) and one categorical dependant variable (genotype pholymorphism), I taught of using ANOVA, but I'm not sure which test to choose and how to find the exact one in SAS.
Thanks in advance!
This is better asked on Cross Validated (https://stats.stackexchange.com/).
That said, I would look at PROC GENMOD or PROC GLM to get an idea of how the genotypes affect the strength variable.
proc genmod data=test;
class genotype ;
model strength = genotype / type1;
run;
You can use PROC TTEST to compare any two levels. Here I compare A to B.
proc ttest data=test(where=(genotype in ('A', 'B')));
class genotype;
var strength;
run;

How does SAS calculate standard errors of coefficients in logistic regression?

I am doing a logistic regression of a binary dependent variable on a four-value multinomial (categorical) independent variable. Somebody suggested to me that it was better to put the independent variable in as multinomial rather than as three binary variables, even though SAS seems to treat the multinomial as if it is three binaries. THeir reason was that, if given a multinomial, SAS would report std errors and confidence intervals for the three binary variables 'relative to the omitted variable', whereas if given three binaries it would report them 'relative to all cases where the variable was zero'.
When I do the regression both ways and compare, I see that nearly all results are the same, including fit statistics, Odds Ratio estimates and confidence intervals for odds ratios. But the coefficient estimates and conf intervals for those differ between the two.
From my reading of the underlying theory,as presented in Hosmer and Lemeshow's 'Applied Logistic Regression', the estimates and conf intervals reported by SAS for the coefficients are consistent with the theory for the regression using three binary independent variables, but not for the one using a 4-value multinomial.
I think the difference may have something to do with SAS's choice of 'design variables', as for the binary regression the values are 0 and 1, whereas for the multinomial they are -1 and 1. But I don't really understand what SAS is doing there.
Does anybody know how SAS's approach differs between the two regressions, and/or can explain the differences in the outputs?
Here is a link to the SAS output:
SAS output
And here is the SAS code:
proc logistic data=tab descending;
class binB binC binD / descending;
model y = binD binC binB ;
run;
proc logistic data=tab descending;
class multi / descending;
model y = multi;
run;